Beckman P/ACE™ MDQ Methods
Development System

Beckman P/ACE™ MDQ Methods
Development System

Multi-format Sample Introduction
Automated Sample Introduction directly from 96 well plates, 2ml autosampler vials, PCR vials and 0.5 ml tubes. Automation is certainly a means by which many laboratory bottle necks may be reduced. One of the major bottle necks is in sample handling. The use of 96 well plates as a sampling vessel not only increases system capacity but allows compatibility with automated sample preparation devices which utilize the 96 well plate format. Additionally, 2 ml vials (which are autosampler industry standards) may be used; or sampling can be achieved directly from PCR vials and microfuge tubes.

Methods Development with 36 Position Buffer Array
Methods Development through a 36 position buffer pair array independent from sampling vials. When optimizing a methods development strategy or scouting for successful separation conditions; the buffer pH, concentration and ion type plays a dramatic role in the process. An array of 36 buffer pairs independent from the samples allows your methods development strategies to be automated while maintaining system sample capacity. To ensure proper separation one must match both the inlet and outlet buffers requiring the necessity of buffer pairs.

Multiple Separation Modes
Modes of separation include: Voltage, Current, Power, Pressure and Vacuum. All electrophoretic separations allow the programming of both step and linear gradients along with the simultaneous application of pressure or vacuum on both ends of the capillary. Voltage gradient programming is beneficial for gel-sieving techniques improving separations over a wide range of fragment sizes. This is especially critical for the separation of nucleic acids. The application of simultaneous voltage and pressure is beneficial for the high efficiency mobilization of proteins during iso-electric focusing as well as detecting material not migrated off the capillary. Also, several CEC methods have specified the use of simultaneous pressure applied to both inlet and outlet reservoir. This system is compatible with those methods.