Beckman LS6000 & LS 6500 Liquid Scintillation Counters
 

The LS 6500 guides you with ease-to-follow menus and context-sensitive help screens. Operate the system without an external computer.

Look at the features this system offers:

Electronics 32,768 Channels Multichannel Analyzer Advanced Photomultiplier Design Interlocking Lead Shielding Motorola Host Processor & Digital Signal Processor

User Interface and Output Monochrome or Color Monitor Windowing User Interface Context-Sensitive Help Screens User-Selectable Output Format

General Automatic Power-Up Diagnostics Automatic Calibration and Verification Diagnostics Program Permanent Memory 336 standard vials and 648 miniature vials Automatic Batch Repeat Bi-Directional Sample Changer Positive Sample Identification Electrostatic Controller

Instrument Editing 20 User Programs Program Protection Isotope Library Interrupt Mode Instrument Parameters Window

Basic Calculations Fixed Background Subtraction First-Vial Blank Subtraction Half-Life Correction to Any Date Final Result Normalization Repeat and Replicate Averaging with %CV Single-Label % of Reference

LSC (liquid scintillation counting) is dependent on the interaction of an energetic particle with an organic compound, the scintillant. This interaction results in a photon(s) which are detected up by a photomultiplier(s) and usually displayed as counts per minute (CPM). Both the LS3801 and LS6500 / LS6000 instruments count samples in a liquid format, either in the standard 20 ml glass or plastic vial or in a 6 ml miniature vial. Only the Model 6500 can be programmed to accurately count dry samples, such as the Beckman ReadyCap. If you are using these insure that you have programmed the instrument properly.

Parameters that you should be prepared to enter include the count time, sample repeat and count channel as well as the radioisotope you are observing. Programs are selected by the use of command cards which are inserted in the first rack. Racks may also be numbered, but this is optional, by the use of special rack number cards. It is possible that a suitable program exists for your application, but confirm that you understand what the program is counting and any calculations it may be performing on your data.

Beckman LS 5000

Beckman LS 6000 and LS 6500
Liquid Scintillation Counter

The current model LS 6500 (and LS6000 for that matter) Scintillation Counter offers unparalleled flexibility in a single high performance system, without the need of a dedicated external computer.  Advanced electronic components, such as a Motorola 68000 Series microprocessor supported by a digital signal processor, maximize technological lifetime and make the LS 6500 fast and efficient.

(NOTE: The specifications, functionality, and styling for the LS 6000 is essentially the same as the LS 6500 at lower cost!)

A 32,768 channel multichannel analyzer gives you an eight-fold improvement in effective resolution (0.06 keV per channel) over that of conventional liquid scintillation counters (0.5 keV per channel). This provides the basis for:

	DPM results without quench curves
	A more precise quench monitor
	Superior results for multi-label studies
	Automatic color detection and correction

Functionally very similar to the LS5801 / LS3801 with additional sophistication. Selection of programs is also accomplished through the use of command cards, but the process of editing user programs is somewhat different.

Additional functionality for the 6500 include improved counting efficiency of dry scintillant (eg ReadyCaps); a reversible belt carrier system that allows for more convenient recounting of samples; counting single racks without command card (under interrupt in the Multi Task menu), single photon counting, and dual label studies. Entering user programs involves selection of isotopes to set spectrometer windows rather that actual window energies. Thus, if you wish to count tritium in channel 1 you would select 3H for isotope one (actually this is the default). If you wish to manually set the window you may do so by entering Manual in this field. Please refer the the manual for detailed instructions.

It is important to note that if are doing a dual labeling study you should choose Isotope 1 as the lower energy isotope and Isotope 2 as the higher energy isotope. The lower limit for Isotope 2 is set the same as the upper limit for Isotope 1. Don't define multiple isotopes in singlely labeled studies as it will result in lowered counts.

Have a Beckman LS counter for sale, we are currently paying cash for LS 6000 series instruments
 

Other LS Counters: Packard TriCarb series

Can't afford the Beckman LS 6500 or LS 6000?

Is all you are doing, wipe tests? ...

You cannot go wrong with the Beckman LS 3801:

       
                      Beckman LS 3801
This instrument can be operated in either a manual or automatic mode. Only the automatic mode is discussed. All racks following will be counted with the protocol defined by the first encountered command card. Counting will stop if the STOP protocol card is encountered. Usually this card is placed into a red rack but the color of rack is immaterial. If a rack is encountered with another command card, before the STOP rack, the new protocol will be used.

To edit user programs, select the appropriate user number after pressing the blue User Number key. While in this screen you may edit count time, sample repeat, select channel to count and set window.

Standard window settings, expressed in channel units are:

	Tritium 0-4000
	l125 0-567
	C13 0-670
	S35 0688
	P32 0-945 for samples in liquid scintillation media
	Cerenkov counting of P32 occurs at much lower energy and is usually counted on the H3 channel (0-400 channels) at an efficiency of about 45% in water.

This very compact benchtop unit is not only reliable, but is fully capable of all of your routine 3H, 14C, 32P assays as well as lab 'wipe tests'.  This is a self-contained easy to operate unit. 

Features:

	H number
	auto quench compensation
	Multi-user programs
	3 counting channels
	Positive Sample ID
	auto calibration & verification
	normalization factor
	half life correction
	sample repeat & replicate averaging
	background subtract
	DPM

Click her for Everything you wanted to know about liquid scintillation counting but were afraid to ask:

  GMI, Inc.
  6511 Bunker Lake Blvd.  
  Ramsey, Minnesota, 55303   USA
  Tel. 763-712-8717          Fax 763-712-8724 
  Send electronic mail to richard@gmi-inc.com