Chrono-log 700 Platelet Aggregometer Model 700

Chrono-log 700 Platelet Aggregometer Model 700

SKU#:
8691-30-0700
  • Rapid and simple diagnostic capability
  • Detect platelet dysfunction in less time
  • Direct luminescent measurement of ATP secretion
  • Sensitive Luminescence Technique

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Description

Chrono-log Whole Blood Lumi/ Blood Optical Lumi- Aggregation Systems improve detection of abnormal platelet function by measuring platelet aggregation and dense granule secretion simultaneously in a physiologic whole blood environment. Efficient and economic the simplicity and heightened sensitivity of whole blood testing allows clinicians to establish a therapeutic monitoring program.

Rapid and Simple Diagnostic Capability
Patients with histories suggestive of hemorrhagic are often investigated for coagulation defects rather than platelet dysfunction because optical aggregation studies are time-consuming and ambiguous.

Now with less than 5mL of blood and in less time than it takes to prepare plasma for tests of coagulation with the Chrono-log Whole Blood Lumi-Aggregation Systems you can detect platelet dysfunction due to:

  • von Willebrand disease
  • Secrection Defects
  • Storage pool deficiency
  • Membrane receptor site defects
  • Non-sterodial anti-inflammatories

For detecting vW disease ristocetin aggregation by the impedance method in whole blood is more reflective of in-vivo conditions than tie-consuming ristocetin co-factor assays in fixed platelets. It is a highly sensitive and time efficient method of screening persons at risk of the disease.

Direct luminescent measurement of ATP secretion in blood provides unequivocal evidence of normal dense granule release and is quantitative measure of platelet activation. In contrast repetitive dose response optical aggregation tests in platelet rich plasma failed to diagnose 67% of patients with storage pool deficiency and a prolonged bleeding time. Simultaneous measurements of the release reaction provides further insight into the mechanisms of platelet response.

Because impedance aggregometry in whole blood is a more adequate tool for detection of platelet hyperaggregability than the optical method patients at risk for thromoboembolic complications can be identified. This greater sensitivity results from performing tests in the presence of red cells and leukocytes.

Patients with a previous history of thrombosis show a high prevalence of platelet hyperactivity. Where the goal of therapy is inhibiting platelet aggregation Chrono-log Whole Blood Aggregometers can routinely identify patients at risk for thromobosis or bleeding and can verify effective treatment.

Aspirin (ASA) is used therapeutically to inhibit thromboxane production of circulating platelets. Monitoring of effective dosage levels of ASA alone or in combination with dipyridamole can be easily performed by measuring platelet aggregation with arachidonic acid or with a low collagen concentration (1ug/mL) and the simultaneous measurement of thromboxane-dependent ATP release.

The coronary vasodilator anti-thrombotic drug Dipyridamole significantly inhibits aggregation in whole blood; this inhibition is not seen in platelet-rich plasma. Interaction between platelets and red blood cells plays an important role in the anti-platelet activity of Dipyridamole.

Sensitive Luminescence Technique

A wide variety of luminescent reactions (ATP release total adenine nucleotides ionized calcium mobilization superoxide generation and others) can be measured by the sensitive photomultipler tube in teh Chrono-log Lumi-Aggregation Systems which provides a voltage output proportional to the luminescence intensity. In addition to detecting Storage Pool and Secretion defects luminescence is also a rapid and sensitive method for detecting Heparin-Induced Thrombocytopenia (HIT).

Services
GMI Certified Service means:
  • Healthy operation of your instrument
  • Helping to ensure the quality of your results
  • Lowering cost of ownership through multilple service agreement options
  • Prolonging instrument serviceable life
  • Safe Operation of your equipment
  • Minimizing downtime increases productivity and minimizes revenue loss
  • Instrument Evaluation Services
  • Contract Refurbishing
  • Relocation Services
  • Equipment Finder Service
  • Training Courses
  • Depot Repair
  • Instrument Decommisioning & Disposal Services
Service Agreements


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Safety
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PM
Preventative Maintenance Visit
('tune up', including cleaning, lubrication, and adjustments)
1PM
or
1 Service Visit
Service Visit 1PM
or
1 Service Visit
1 2
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Parts and Labor    

1 YEAR
Discounted Parts
Discounted Labor (As needed)
Parts

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WHY BUY FROM GMI?

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  • We routinely save discerning laboratories 30-80% with our recertified pre-owned and factory clearance instrument offerings.

  • Quality? ISO 9001:2008 certified means we remove 100% of the risk in buying ‘used’ laboratory equipment.

  • Warranties from 90 days to a year as well as multi-year service agreements are available.

GMI is an ISO 9001:2008 certified company - proof that your instruments pass through a rigorous re-certification process to ensure that it arrives at your laboratory defect-free and in full working order.
We are neither an auction company nor an instrumentation broker. GMI employs our own factory-trained engineers to ensure full control of this process.
Unlike small-time businesses and brokers, GMI goes beyond offering money-back promises. We offer real product warranties.
Apart from our meticulous inspection processes, GMI’s available warranties and multi-year service agreements guarantee customer satisfaction - no need to go through frustrating and time-consuming product returns!
Additionally, all items are thoroughly cleaned and professionally packaged/crated with care to insure they arrive in your lab ready for use.