New Brunswick BioFlo 110 Fermentor

New Brunswick BioFlo 110 Fermentor

  • Interchangeable control modules, impellers, motor drives and vessels
  • Pre-programmed control ranges
  • Control and view up to four separate vessels from a single screen
  • Built-in “cascade” feature
  • Adjustable P-I-D values for pH and DO

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New Brunswick's BioFlo 110 Modular Fermentor & Bioreactor is versatile enough to meet specific laboratory needs. This powerful model was designed to simplify procedures for hassle-free processing. As a result, demanding laboratories are able to increase biomass yields to keep up with dynamic research requirements.

The BioFlo 110 fermentor automates procedures to ensure the accuracy and reliability of results. Operators can set points for both pH and dissolved oxygen (DO), which can be automatically maintained with this modular fermentor. Users can control pH through gas, acid or base addition with the cascade feature. Gas or addition agitations can be also used for DO manipulation. Users can also increase control flexibility by adjusting P-I-D values for both pH and DO.

Equipment operators have an option to use a manual rotameter or a digital mass flow control for gas flow management. New Brunswick adapters also provide a wide range of options by adjusting probe immersion lengths. Magnetic drive and direct drive options are also available for cell culture applications. Fermentation processes make use of the direct drive as a standard.

New Brunswick also enhanced control and the data logging efficiency of the BioFlo 110 modular fermetor & bioreactor with the NBS BioCommand® software and its Modbus compatibility.

Call us today to learn more about the New Brunswick BioFlo 110 Modular Fermentor & Bioreactor!


New Brunswick BioFlo 110 Fermentor Specifications

Total Volume1.3 Liters3.0 Liters7.5 Liters14.0 Liters
Working Volume0.4 – 1.0 Liters0.8 – 2.2 Liters2.0 – 5.6 Liters4.0 – 10.5 Liters
DesignWater-jacketed and heat-blanketed vessels available.
All are autoclavable, dished-bottom, borosilicate glass.
FermentationDirect drive, 50 – 1,200 rpm, dual Rushton-style impellers
Cell Culture30 – 300 rpm, direct or magnetic drive, pitched blade impeller
ControlAll vessels use P-I-D control for heating and cooling
Heat-Blanketed Vessels: External heat mantle & high-capacity immersed cooling coil
Water-Jacketed Vessels: Temperature-controlled water in glass jacket
Maximum Temp.70° C
Controller DesignPrimary Control Unit (PCU) plus optional, stackable loop-control modules.
PCU supports 4 vessels — up to 32 loops, total
CommunicationsSerial Port with BioCommand & Modbus protocols.
4-channel 0 - 2.5 V DC output for recorder
Primary Control Unit (PCU)
FunctionsHuman Interface Control Center for up to 4 vessels
DisplayBright text & graphics on 3.4 x 4.5”
(8.6 x 11.4 cm) 1⁄4 VGA screen
Automatically senses attached loop controllers
UpgradesBuilt-in floppy drive for easy firmware upgrades
Display LanguagesEnglish, German, French & Spanish
Control ModesManual and Automatic
Operating ModesFermentation and Cell Culture
Power ControllerProvides power for temperature control (heating and cooling),
agitation and 5 optional pumps for liquid addition and removal
4-Pump ModuleModule provides four peristaltic
pumps for liquid addition and removal
Antifoam/ Levels ControllerModule supports three conduction probes for
automating liquid additions and removals, and foam control
DO₂- pH Controller
General InfoOptional controller with one pH
and one dissolved oxygen (DO) probe connection
Oxygen Control
Setpoint range: 0 – 100 %. Agitation or oxygen enrichment cascades.
Sparge on demand. Four-gas algorithm for cell culture application
pH ControlSetpoint range: 2 – 12. Control - P-I-D with adjustable deadband.
Acid/baseliquid additions (requires pumps).
Four-gas mixing (requires Gas Mix Controller)
Gas Mix ControllerFour solenoid valves sequence additions of up to four gasses
for pH and DO control in cell culture,
or oxygen enrichment of sparge gasses
Utility Requirements
Water (50µ filter)5–10 PSIG (0.34– 0.68 kg/cm²)
Air/O₂/CO₂/N₂3–10 PSIG (0.20– 0.68 kg/cm²) medical grade
Electricity(2) 100/120V, 50/60 Hz, 10 Amp or
(2) 200/240V, 50/60 Hz, 6 Amp
CertificationsCE, cETL
Simplified OrderingA variety of complete kits are offered

Autoclave Glass Vessels sizes
(total volume)
1.3, 3.0, 7.5 and 14.0 (L)
Vessel choices
(available in 1.3, 3.0,
7.5 and 14L options)
  • single-wall vessel with heat blanket
  • double-walled vessel with water-jacket heater
Available Kits
  • Basic fermentation
  • Advanced fermentation
  • Advanced cell culture
Controllers and componentsOptional
Gas Mix ControllerOptional
(Automatically mixes 2 to 4 gasses for optimized
growth in microbial, insect and animal cell cultures)
GMI Certified Service means:
  • Healthy operation of your instrument
  • Helping to ensure the quality of your results
  • Lowering cost of ownership through multilple service agreement options
  • Prolonging instrument serviceable life
  • Safe Operation of your equipment
  • Minimizing downtime increases productivity and minimizes revenue loss
  • Instrument Evaluation Services
  • Contract Refurbishing
  • Relocation Services
  • Equipment Finder Service
  • Training Courses
  • Depot Repair
  • Instrument Decommisioning & Disposal Services
Service Agreements

Preventative Maintenance Visit
('tune up', including cleaning, lubrication, and adjustments)
1 Service Visit
Service Visit 1PM
1 Service Visit
1 2
Parts and Labor    

Discounted Parts
Discounted Labor (As needed)

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